John Francis Crowley is an American biotechnology executive and entrepreneur. He is best-known as the founder of several biotech companies devoted to curing genetic diseases. After his two youngest children were diagnosed with Pompe Disease, Crowley became the CEO of Oklahoma City-based Novazyme, a biotechnology start-up that was conducting research on a new experimental treatment for the disease. His story has been made into the new movie with Brendan Fraser and Harrison Ford, “Extraordinary Measures.”